VisANT: data-integrating visual framework for biological networks and modules.

VisANT: data-integrating visual framework for biological networks and modules.
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DOI:
10.1093/nar/gki431
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发表时间:
2005-07-01
影响因子:
14.9
通讯作者:
Delisi C
Delisi C
中科院分区:
生物学2区
文献类型:
--
作者:
Hu Z;Mellor J;Wu J;Yamada T;Holloway D;Delisi C

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VisANT是一个基于Web的软件框架,用于可视化和分析许多类型的生物相互作用和关联网络。网络是一种有用的计算工具,用于表示许多类型的生物数据,如生物分子相互作用,细胞通路和功能模块。给定用户定义的基因或蛋白质之间的相互作用或分组集,VisANT提供:(i)用于组合和注释网络数据的可视化界面,(ii)支持来自Gene Ontology和KEGG数据库的不同基因组的功能和注释数据,以及(iii)提取用户定义网络的拓扑特性所需的统计和分析工具。用户可以自定义、修改、保存和与其他用户共享网络视图,并从自己的数据源以及标准交换格式(如PSI-MI和BioPAX)导入基本网络数据表示。我们所采用的软件架构,亦透过其开放式API,为以Java为基础的插件,支援更复杂的可视化及分析功能的开发。VisANT可透过互联网免费派发,网址为,亦可供个人下载使用。
VisANT is a web-based software framework for visualizing and analyzing many types of networks of biological interactions and associations. Networks are a useful computational tool for representing many types of biological data, such as biomolecular interactions, cellular pathways and functional modules. Given user-defined sets of interactions or groupings between genes or proteins, VisANT provides: (i) a visual interface for combining and annotating network data, (ii) supporting function and annotation data for different genomes from the Gene Ontology and KEGG databases and (iii) the statistical and analytical tools needed for extracting topological properties of the user-defined networks. Users can customize, modify, save and share network views with other users, and import basic network data representations from their own data sources, and from standard exchange formats such as PSI-MI and BioPAX. The software framework we employ also supports the development of more sophisticated visualization and analysis functions through its open API for Java-based plug-ins. VisANT is distributed freely via the web at and can also be downloaded for individual use.