A longitudinal-torsional mode ultrasonic needle for deep penetration into bone.
A longitudinal-torsional mode ultrasonic needle for deep penetration into bone.
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DOI：
10.2139/ssrn.4000262
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发表时间：
2022-05
期刊：
影响因子：
4.2
通讯作者：
R. Cleary;Robert Wallace;H. Simpson;G. Kontorinis;M. Lucas
中科院分区：
文献类型：
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作者：
R. Cleary;Robert Wallace;H. Simpson;G. Kontorinis;M. Lucas
本文介绍了一种用于骨深穿透的螺旋-扭转（L-T）复合模式超声针装置。L-T穿刺针是L型穿刺针的几何改良版本，其作为原型超声骨活检器械的有效性已由作者先前证明。有限元分析（FEA）辅助L-T缝针的设计，旨在最大化可实现的扭转位移，同时匹配L模式缝针实现的纵向位移。利用实验模态分析（EMA）对所制作的超声器件进行模态参数识别，验证有限元模型的正确性。谐波分析，然后提供了一个洞察的固有的非线性的高功率换能器的影响，将退化的L模式到L-T模式的几何特征。高功率特性表明，L-T模式针的纵向位移幅度大于L模式针的纵向位移幅度。通过研究细胞死亡和细胞存活来评价新鲜Wistar大鼠颅骨中的比较穿透试验。两种器械的统计学显著性细胞死亡区域均较小，L-T器械的轴向和剪切运动导致该区域内骨细胞坏死增加。然而，结果表明，一个有希望的环境，术后愈合。它显示了这项技术如何提供一种潜在的技术，为手术方法的岩尖，应用程序，需要深入到骨。
This work presents a longitudinal-torsional (L-T) composite mode ultrasonic needle device for deep bone penetration. The L-T needle is a geometrically modified version of an L-mode needle whose efficacy as a prototype ultrasonic bone biopsy device has been previously demonstrated by the authors. Finite element analysis (FEA) aided in the design of the L-T needle, with the aim of maximising the achievable torsional displacement while matching the longitudinal displacement achieved by the L-mode needle. Experimental modal analysis (EMA) of the fabricated ultrasonic device was used to identify the modal parameters and validate the FEA model. Harmonic analysis then provided an insight into how the inherent nonlinearities of the high-power transducer are affected by incorporating the geometrical features that degenerate the L mode into an L-T mode. High power characterisation shows that the longitudinal displacement amplitude of the L-T mode needle is larger than that of the L-mode needle. Comparative penetration tests in fresh Wistar rat skull were evaluated by investigating cell death and cell survival. The region of statistically significant cell death was small for both devices, with the combined axial and shear motion of the L-T device causing increased osteocyte necrosis within this region. Nevertheless, the results suggest a promising environment for post-operative healing. It is shown how this technology offers a potential technique for a surgical approach to the petrous apex, an application that requires a deep penetration into bone.