Do-it-yourself biology: challenges and promises for an open science and technology movement.
Do-it-yourself biology: challenges and promises for an open science and technology movement.
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DOI：
10.1007/s11693-013-9116-4
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发表时间：
2013-09-01
期刊：
影响因子：
--
通讯作者：
Sussan, Remi
中科院分区：
文献类型：
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作者：
Landrain, Thomas;Meyer, Morgan;Sussan, Remi
diy生物学（DIYbio）社区正在兴起，作为一种运动，它促进了现代分子生物学和合成生物学等资源的开放获取。它尤其有望为环境监测、个人诊断和生物材料的使用提供更便宜、更简单的解决方案。DIYbio从业者全球社区的成功发展将在很大程度上取决于能否安全获得最先进的分子生物学工具和资源。本文分析了DIYbio的兴起、DIYbio的群体、DIYbio的材料资源和DIYbio的应用。我们着眼于目前为国际基因工程机器竞赛开发的项目，以便了解业余生物学家在未来几年可能在他们的社区实验室中创造什么。我们还展示了在全球治理发展的背景下，DIYbio社区为什么以及如何建立一个安全/道德框架，以保证其活动的开展。最后，我们认为，DIY生物学的全球传播可能会重新配置并开放对生物信息和实验室设备的访问，因此，它可以促进专业科学家和业余爱好者之间的新实践和横向合作。
The do-it-yourself biology (DIYbio) community is emerging as a movement that fosters open access to resources permitting modern molecular biology, and synthetic biology among others. It promises in particular to be a source of cheaper and simpler solutions for environmental monitoring, personal diagnostic and the use of biomaterials. The successful growth of a global community of DIYbio practitioners will depend largely on enabling safe access to state-of-the-art molecular biology tools and resources. In this paper we analyze the rise of DIYbio, its community, its material resources and its applications. We look at the current projects developed for the international genetically engineered machine competition in order to get a sense of what amateur biologists can potentially create in their community laboratories over the coming years. We also show why and how the DIYbio community, in the context of a global governance development, is putting in place a safety/ethical framework for guarantying the pursuit of its activity. And finally we argue that the global spread of DIY biology potentially reconfigures and opens up access to biological information and laboratory equipment and that, therefore, it can foster new practices and transversal collaborations between professional scientists and amateurs.