Polar encapsidation of adenovirus DNA: cloning and DNA sequence of the left end of adenovirus type 3.

Polar encapsidation of adenovirus DNA: cloning and DNA sequence of the left end of adenovirus type 3.
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腺病毒 DNA 的极性包壳:3 型腺病毒左端的克隆和 DNA 序列。

DOI:
10.1128/jvi.43.3.1132-1137.1982
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发表时间:
1982
影响因子:
5.4
通讯作者:
Tibbetts,C
Tibbetts,C
中科院分区:
医学2区
文献类型:
--
作者:
Kosturko,LD;Sharnick,SV;Tibbetts,C

文献摘要

相似文献

左端腺病毒3型DNA序列与其他B亚型腺病毒非常相似,特别是在HinfI位点(320个碱基对)和早期区域Ia基因之间的区域。基因组的这一段被认为是腺病毒DNA包装的左端所必需的。将该片段及其两侧的序列与5型腺病毒和12型腺病毒的相应序列进行比较,并讨论了亚组间同源性的程度和模式。
The left-end adenovirus type 3 DNA sequence is very similar to those of other subgroup B adenoviruses, especially in the area between the HinfI site (320 base pairs) and the early-region Ia gene. This segment of the genome has been implicated as necessary for the left-end polarity of adenovirus DNA encapsidation. This segment and the sequences flanking it are compared with the corresponding sequences of adenovirus type 5 and adenovirus type 12, and the extent and pattern of intersubgroup homologies are discussed.