Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye
Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye
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DOI：
10.1016/s0140-6736(96)91685-2
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发表时间：
1996-05-25
期刊：
影响因子：
168.9
通讯作者：
Parkin, DM
中科院分区：
文献类型：
--
作者：
Newton, R;Ferlay, J;Parkin, DM
背景我们调查了眼部鳞状细胞癌的地理分布，以评估太阳紫外线是否是该病的危险因素。方法我们使用常规收集的基于人群的癌症发病率数据和公布的环境太阳紫外线测量进行分析。结果发现，纬度每升高10度(p50度)，眼部鳞状细胞癌的发病率下降49%。太阳紫外线辐射随着纬度的增加而减少，每单位紫外线照射减少眼鳞状细胞癌的发病率29%(p
Background We have investigated the geographic distribution of squamous-cell carcinoma of the eye to assess whether solar ultraviolet light is a risk factor for this disease.Methods We used routinely collected population-based cancer incidence data and published measurements of ambient solar ultraviolet light in our analysis.Findings The incidence of squamous-cell carcinoma of the eye declined by 49% for each 10 degrees increase in latitude (p50 degrees). Solar ultraviolet radiation decreases with increasing latitude, and the incidence of squamous-cell carcinoma of the eye decreased by 29% per unit reduction in ultraviolet exposure (p