Selective neural sensitivity to familial threat in adolescents with weak family bonds.
Selective neural sensitivity to familial threat in adolescents with weak family bonds.
复制标题
家庭纽带薄弱的青少年对家庭威胁的选择性神经敏感性。
DOI：
10.1080/17470919.2017.1397545
复制
发表时间：
2019
影响因子：
2
通讯作者：
Telzer,EvaH
中科院分区：
文献类型：
--
作者：
Sharp,PaulB;Heller,Wendy;Telzer,EvaH
家庭的压力，如弱的家庭连通性，与适应不良的威胁处理的发展，但鲜为人知的是，弱的家庭债券如何影响威胁处理的生物机制。本研究利用功能磁共振成像数据的多体素模式分析，以比较神经编码的家庭和非家庭的威胁和非威胁性的刺激，在青少年谁赞同不同程度的连接到他们的家庭。青少年（N = 22，法师= 14.38岁）报告较低的家庭联系1年前表现出较高的敏感性，家庭的威胁，但不与威胁处理相关的神经网络，包括左，右杏仁核，右颞下回和中颞回的非家族性威胁。研究结果表明，一个人的社会环境的学习历史可能会塑造威胁处理的神经机制，使他们敏感的风险相关的刺激。这些发现推进了我们对家庭压力如何导致青春期威胁处理障碍的理解。
Familial stressors, such as weak familial connectedness, are associated with the development of maladaptive threat processing, yet little is known regarding how weak familial bonds impinge on biological mechanisms of threat processing. The present study leveraged multivoxel pattern analysis of fMRI data to compare the neural encoding of familial and nonfamilial threatening and non-threatening stimuli in adolescents who endorsed varying levels of connectedness to their families. Adolescents (N = 22, Mage = 14.38 years) reporting lower family connectedness 1 year earlier showed elevated sensitivity to familial threat, but not to nonfamilial threat in a neural network associated with threat processing, comprising left and right amygdala, and right inferior and middle temporal gyri. Results suggest that a learning history about one’s social environment may shape neural mechanisms of threat processing by sensitizing them to risk-relevant stimuli. Such findings advance our understanding of how familial stressors contribute to disordered threat processing in adolescence.