Safety of probiotics.

Safety of probiotics.
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DOI:
10.1080/11026480410026447
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发表时间:
2004-01-01
期刊:
Scandinavian Journal of Nutrition
影响因子:
--
通讯作者:
Salminen, S.
Salminen, S.
中科院分区:
其他
文献类型:
--
作者:
Gueimonde, M.;Ouwehand, A. C.;Salminen, S.

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益生菌在食品中的使用显著增加,有越来越多的产品含有大量可存活的益生菌。本文对益生菌的安全性信息进行了综述。对当前益生菌的安全性数据进行了文献检索和评估。没有观察到当前益生菌的重大安全问题。现有数据证明了乳酸菌和双歧杆菌益生菌的安全性。总而言之,目前的益生菌被认为是安全的食品使用,也有很长的安全使用历史和上市后监测数据。然而,需要对新型益生菌,特别是转基因益生菌进行严格的安全性评估。
The use of probiotics in foods has increased significantly and there are more and more products available with high numbers of viable probiotics. This article reviews the safety information on probiotic microorganisms. A literature search and assessment of safety data on current probiotics were undertaken. No significant safety concerns for current probiotics were observed. The available data attest to the safety of Lactobacillus and Bifidobacterium probiotics. In conclusion, current probiotics are considered safe for food use and also have a long history of safe use with postmarket monitoring data available. However, rigorous safety assessment for novel probiotics and especially genetically modified probiotics needs to be established.