Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components
Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components
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DOI：
10.1017/s0007114507750882
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发表时间：
2007-10-01
影响因子：
3.6
通讯作者：
Lafuente, Amalia
中科院分区：
文献类型：
--
作者：
Laso, Nuria;Brugue, Emma;Lafuente, Amalia
共轭亚油酸（CLA）对人体体重和体成分的影响存在争议。本研究的目的是探讨牛奶中添加共轭亚油酸对机体组成和代谢综合征的生化指标的影响。这是一项随机、双盲、安慰剂对照试验。受试者被随机分配至每日摄入500 ml补充有3 g CLA的牛奶（使用生物活性异构体顺式-9，反式-11和反式-10，顺式-12的混合物，销售名称为Tonalino（（R）），Naturlinea; Central Lechera Asturiana）或安慰剂，持续12周。60名有代谢综合征体征的健康男性和女性（年龄35-65岁）参与研究（BMI 25-35 kg/m2）。使用双能X线吸收测定法测量身体组成（第0周基线和第12周）。具有BMI的CLA-牛奶亚组中的总脂肪量
The effects of conjugated linoleic acid (CLA) on body weight and body composition in man are controversial. The aim of this study was to investigate the effects of milk supplementation with CLA on body composition and on the biochemical parameters of the metabolic syndrome. This was a randomised, double-blind, placebo-controlled trial. Subjects were randomised to a daily intake of 500 ml milk supplemented with 3 g CLA (using a mixture of the bioactive isomers cis-9, trans-11 and trans-10, cis-12, marketed as Tonalino((R)), Naturlinea; Central Lechera Asturiana) or placebo for 12 weeks. Sixty healthy men and women (aged 35-65 years) with signs of the metabolic syndrome participated (BMI 25-35 kg/m(2)). Dual-energy X-ray absorptiometry was used to measure body composition (week 0 baseline and week 12). Total fat mass in the CLA-milk subgroup with a BMI