Reiterated Wnt and BMP signals in neural crest development.
Reiterated Wnt and BMP signals in neural crest development.
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重申神经嵴发育中的 Wnt 和 BMP 信号。
DOI：
10.1016/j.semcdb.2005.06.008
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发表时间：
2005
影响因子：
7.3
通讯作者：
Ragland,JaredW
中科院分区：
文献类型：
--
作者：
Raible,DavidW;Ragland,JaredW
常见的信号传导途径，如Wnt和BMP的信号传导途径，在胚胎发生过程中多次使用。在神经嵴的发育过程中，Wnt和BMP信号在不同阶段重复使用，以影响初始诱导、从神经上皮分离和细胞命运决定。这篇评论认为，特异性是如何产生的神经嵴内的这些重申的信号，讨论的例子，信号事件的结果是如何调制的上下文。
Common signaling pathways such as those for Wnts and BMPs are used many times during embryogenesis. During the development of the neural crest, Wnt and BMP signals are used repeatedly at different stages to influence initial induction, segregation from the neuroepithelium and cell fate determination. This review considers how specificity is generated within the neural crest for these reiterated signals, discussing examples of how the outcomes of signaling events are modulated by context.