Development of a European Human Embryonic Stem Cell Registry
Development of a European Human Embryonic Stem Cell Registry
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DOI：
10.2217/17460751.3.6.945
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发表时间：
2008-11-01
影响因子：
2.7
通讯作者：
Veiga, A.
中科院分区：
文献类型：
--
作者：
Borstlap, J.;Kurtz, A.;Veiga, A.
可用的人类胚胎干细胞（hESC）系的数量正在稳步增加，并随后被用于许多研究项目。然而，hESC细胞系衍生的协调很少，关于这些细胞的特性和质量的比较信息也很少。获得关于hESCs的一致信息进一步受到立法分裂的阻碍，特别是在欧洲。认识到这些障碍，欧盟委员会已经建立了人类胚胎干细胞登记（hESCreg），使hESCs及其特征信息可访问，并确保研究结果能够更快地向公众提供。hESCreg的主要目标是提供有关现有hESC细胞系及其衍生、分子特征、使用和质量的免费信息。成功的hESC细胞系研究将用于评估临床潜力，从而直接影响政策决策。与其他倡议，如鉴定项目、登记和细胞库的发展整合，预计将导致一个共同的和国际上接受的中心参考。hESCreg向这个方向迈出了第一步，并可能发展成为一个国际资助和管理的项目。
The number of human embryonic stem cell (hESC) lines that are available and that are subsequently being used in numerous research projects is increasing steadily. However, there is little coordination of hESC line derivation, and comparative information on the characteristics and quality of these cells is sparse. Obtaining consistent information on hESCs is hampered further by legislative fragmentation, particularly in Europe. Recognizing these obstacles, the European Commission has set up a Human Embryonic Stem Cell Registry (hESCreg) to make hESCs and their characterizing information accessible and to ensure that the results of research become more quickly available to the public. The primary objectives of hESCreg are to provide freely accessible information on existing hESC lines, their derivation, molecular characteristics, use and quality. Successful research with listed hESC lines will be used to evaluate clinical potential and thus directly influence policy decisions. The developing integration with other initiatives, such as characterization projects, registries and cell banks, is expected to lead to a common and internationally accepted central reference. The hESCreg provides a first step in this direction and might grow into an internationally funded and administered project.