Comparative study for N and S doped carbon dots: Synthesis, characterization and applications for Fe3+ probe and cellular imaging
Comparative study for N and S doped carbon dots: Synthesis, characterization and applications for Fe3+ probe and cellular imaging
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N 和 S 掺杂碳点的比较研究：Fe3 探针和细胞成像的合成、表征和应用
DOI：
10.1016/j.aca.2015.09.050
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发表时间：
2015-10-22
影响因子：
6.2
通讯作者：
Dong, Chuan
中科院分区：
文献类型：
--
作者：
Lu, Wenjing;Gong, Xiaojuan;Dong, Chuan
以DL-苹果酸为碳源，乙醇胺和乙磺酸分别为氮、硫掺杂剂，采用微波辅助热分解法一步制备了氮、硫掺杂的碳量子点。通过对碳量子点的形貌、化学结构和光学性质的研究，发现所制备的碳量子点具有良好的发光稳定性、抗光漂白性和良好的溶解性。与未掺杂的CD相比，加入N或S掺杂剂可以使CD的粒径稍小，荧光寿命较长。此外，由于其在水中的良好分散性、激发依赖性发射、优异的生物相容性和低毒性，最佳N-CD被成功地用作良好的细胞成像探针。此外，N-CD作为Fe 3+的荧光探针，具有较宽的检测范围和较高的准确度。该探针能够选择性地检测Fe 3+离子，线性范围为6.0-200 μ M，检测限为0.80 μ M。(C)2015 Elsevier B. V.版权所有。
A facile and eco-friendly approach to prepare nitrogen(N)- and sulfur(S)-doped carbon dots (CDs) by one step microwave-assisted pyrolysis of the precursors with DL-malic acid as carbon source, ethanolamine and ethane-sulfonic acid as N and S dopants, respectively, was reported. Through the extensive investigation on morphology, chemical structures and optical properties of the carbon dots, it was found that the obtained CDs exhibited good luminescence stability, high resistance to photo bleaching and favorite solubility. Compared with undoped CDs, adding the N or S dopant could give rise to a slightly smaller particle size and a long fluorescence lifetime of CDs. Moreover, the optimal N-CDs was successfully employed as good multicolor cell imaging probes due to its fine dispersion in water, excitation-dependent emission, excellent biocompatibility and low toxicity. Besides, such N-CDs showed a wide detection range and excellent accuracy as fluorescent probe for Fe3+ ions. This probe enabled the selective detection of Fe3+ ions with a linear range of 6.0-200 mu M and a limit of detection of 0.80 mu M. (C) 2015 Elsevier B.V. All rights reserved.