Control of cell proliferation by Myc

Control of cell proliferation by Myc
复制标题

DOI:
10.1016/s0962-8924(98)01251-3
复制
发表时间:
1998-05-01
影响因子:
19
通讯作者:
Eilers, M
Eilers, M
中科院分区:
生物学1区
文献类型:
--
作者:
Bouchard, C;Staller, P;Eilers, M

文献摘要

被引文献

相似文献

Myc 蛋白是哺乳动物细胞增殖的关键调节因子。它们是转录因子,可激活基因,作为与 Max 蛋白形成异二聚体复合物的一部分。这篇综述总结了了解 Myc 如何刺激细胞增殖以及这如何促进细胞转化和肿瘤发生的最新进展。
Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis.