Control of cell proliferation by Myc
Control of cell proliferation by Myc
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DOI:
10.1016/s0962-8924(98)01251-3
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发表时间:
1998-05-01
影响因子:
19
通讯作者:
Eilers, M
中科院分区:
文献类型:
--
作者:
Bouchard, C;Staller, P;Eilers, M
Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis.