Effect of Long-Term Formalin Preservation on the Bending Properties and Fracture Toughness of Bovine Compact Bone
Effect of Long-Term Formalin Preservation on the Bending Properties and Fracture Toughness of Bovine Compact Bone
复制标题
福尔马林长期保存对牛致密骨弯曲性能和断裂韧性的影响
DOI：
10.2320/jinstmet.69.267
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发表时间：
2005
影响因子：
--
通讯作者：
T. Asaka
中科院分区：
文献类型：
--
作者：
Hisao Kikugawa;T. Asaka
为了精确确定骨骼的机械性能，需要尽量减少保存方法对其机械性能的影响。长时间接触福尔马林（甲醛溶液）似乎会对骨的机械性能产生一些影响。本研究探讨了福尔马林固定方法对牛皮质骨短期和相对长期保存后弯曲性能和断裂韧性的影响。为了确定从骨洗脱到福尔马林溶液（保存介质）中的元素和数量，通过电感耦合等离子体原子发射光谱（ICP-AES）进行定性和定量分析。福尔马林固定增强了皮质骨的弯曲刚度，同时降低了其断裂韧性。由于弯曲强度随着 Ca2+ 的去除而同时减弱，这意味着骨的无机成分有助于其弯曲强度。
To precisely determine the mechanical properties of a bone, the effects of the preservation method on its mechanical properties need to be minimized. It seems likely that prolonged exposure to formalin (formaldehyde solution) will have some affect the mechanical properties of bone. This study investigated the effect of the formalin fixation method on the bending properties and fracture toughness of bovine cortical bone after short-term and relatively long-term preservation. To determine the elements and the quantities eluted from bone into formalin solution (the preservation medium), qualitative and quantitative analyses were performed by inductively coupled plasma atomic emission spectroscopy (ICP-AES). Formalin fixation augments the bending stiffness of the cortical bone while diminishing its fracture toughness. As the bending strength diminishes concurrently with removal of Ca2+, this implies that inorganic components of bone contribute to its bending strength.