Proposed minimum reporting standards for chemical analysis
Proposed minimum reporting standards for chemical analysis
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DOI：
10.1007/s11306-007-0082-2
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发表时间：
2007-09-01
期刊：
影响因子：
3.6
通讯作者：
Viant, Mark R.
中科院分区：
文献类型：
--
作者：
Sumner, Lloyd W.;Amberg, Alexander;Viant, Mark R.
人们普遍认为，需要对描述大规模代谢组学和其他功能基因组学数据集的元数据或信息进行标准化报告。标准元数据的报告为数据提供了生物学和经验背景，促进了实验复制，并使其他人能够重新询问和比较数据。因此，代谢组学标准倡议正在就代谢组学实验的最低报告标准建立普遍共识，化学分析工作组（CAWG）是该社区努力的成员之一。本文提出了与代谢组学实验的化学分析相关的最低报告标准，包括：样品制备、实验分析、质量控制、代谢物鉴定和数据预处理。这些最低标准目前主要集中在质谱和核磁共振波谱上，因为这些技术在代谢组学中的普及。但是，欢迎有关其他技术的额外输入，并可通过CAWG在线讨论论坛http://msi-workgroups.sourceforge.net/或http://Msi-workgroups-feedback@lists.sourceforge.net提供。此外，还可以通过这个电子论坛提供与本文件有关的社区输入。
There is a general consensus that supports the need for standardized reporting of metadata or information describing large-scale metabolomics and other functional genomics data sets. Reporting of standard metadata provides a biological and empirical context for the data, facilitates experimental replication, and enables the re-interrogation and comparison of data by others. Accordingly, the Metabolomics Standards Initiative is building a general consensus concerning the minimum reporting standards for metabolomics experiments of which the Chemical Analysis Working Group (CAWG) is a member of this community effort. This article proposes the minimum reporting standards related to the chemical analysis aspects of metabolomics experiments including: sample preparation, experimental analysis, quality control, metabolite identification, and data pre-processing. These minimum standards currently focus mostly upon mass spectrometry and nuclear magnetic resonance spectroscopy due to the popularity of these techniques in metabolomics. However, additional input concerning other techniques is welcomed and can be provided via the CAWG on-line discussion forum at http://msi-workgroups.sourceforge.net/ or http://Msi-workgroups-feedback@lists.sourceforge.net. Further, community input related to this document can also be provided via this electronic forum.