Which criteria should be used to define type 2 diabetes remission after bariatric surgery?

Which criteria should be used to define type 2 diabetes remission after bariatric surgery?
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DOI:
10.1186/1471-2482-13-8
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发表时间:
2013-03-28
期刊:
影响因子:
1.9
通讯作者:
Rubio, Miguel A.
Rubio, Miguel A.
中科院分区:
医学4区
文献类型:
--
作者:
Ramos-Levi, Ana M.;Cabrerizo, Lucio;Rubio, Miguel A.

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背景资料:采用两种不同模型的criteris.Methods:回顾性分析110例2型糖尿病和病态肥胖患者接受减肥手术,术前和18个月随访的数据。两种缓解模型的比较:1)2009年共识声明标准; 2)使用ADA的HbA 1c糖尿病诊断临界值的简单标准。结果:患者的平均+/- SD术前特征为:年龄53.3 ± 9.5岁,BMI 43.6 ± 5.5 kg/m2,HbA 1c 7.9 ± 1.8%,糖尿病病程7.6 ± 7.5年。44.5%的患者既往接受过胰岛素治疗。与2009年共识声明标准:完全,部分和无缓解分别为50%,12.7%和37.3%,与HbA 1c标准:50%,15%和34.5%的类似类别(p = 0.673)。结论:我们建议一个更简单的方法来评估减肥手术后糖尿病缓解,以下的糖尿病本身的定义的基本原理。
Background: Comparison of diabetes remission rates after bariatric surgery using two different models of criteria.Methods: Retrospective analysis of data from 110 patients with type 2 diabetes and morbid obesity who underwent bariatric surgery, preoperatively and at 18-month follow-up. Comparison of two models of remission: 1) 2009 consensus statement criteria; 2) simple criteria using ADA's HbA1c diabetes diagnostic cut-off values.Results: Patients' mean +/- SD preoperative characteristics were: age 53.3 +/- 9.5 years, BMI 43.6 +/- 5.5 kg/m(2), HbA1c 7.9 +/- 1.8%, duration of diabetes 7.6 +/- 7.5 years. 44.5% of patients with previous insulin therapy. With 2009 consensus statement criteria: complete, partial and no remission in 50%, 12.7% and 37.3%, respectively; with HbA1c criteria: 50%, 15% and 34.5% in the analogous categories (p = 0.673).Conclusions: We suggest a simpler approach to evaluate diabetes remission after bariatric surgery, following the rationale of the definition of diabetes itself.