Making it to the synapse: measles virus spread in and among neurons.

Making it to the synapse: measles virus spread in and among neurons.
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使其成为突触:麻疹病毒在神经元中及其中扩散。

DOI:
10.1007/978-3-540-70617-5_1
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发表时间:
2009
影响因子:
--
通讯作者:
--
中科院分区:
医学3区
文献类型:
--
作者:

文献摘要

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Measles virus (MV) is one of the most transmissible microorganisms known, continuing to result in extensive morbidity and mortality worldwide. While rare, MV can infect the human central nervous system, triggering fatal CNS diseases weeks to years after exposure. The advent of crucial laboratory tools to dissect MV neuropathogenesis, including permissive transgenic mouse models, the capacity to manipulate the viral genome using reverse genetics, and cell biology advances in understanding the processes that govern intracellular