Neural plasticity after human spinal cord injury: Application of locomotor training to the rehabilitation of walking
Neural plasticity after human spinal cord injury: Application of locomotor training to the rehabilitation of walking
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DOI：
10.1177/107385840100700514
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发表时间：
2001-10-01
期刊：
影响因子：
5.6
通讯作者：
Harkema, SJ
中科院分区：
文献类型：
--
作者：
Harkema, SJ
在临床上完全性或严重不完全性脊髓损伤后，即使经过常规治疗，运动恢复也被认为是不可能实现的。然而，脊髓动物的运动可以通过训练来改善，训练提供与由脊髓解释的步进相关的感觉信息的复杂时间模式。这篇综述讨论了表明人类脊髓网络可以整合和解释复杂的感觉信号以产生功能性传出输出并适应重复训练的证据。运动训练是一种新的康复方法，其原理是促进四肢和躯干的运动，产生与运动一致的感觉信息，以提高神经损伤后步行的恢复潜力。
Recovery of locomotion has been considered unattainable following a clinically complete or severe incomplete spinal cord injury even after conventional therapy. However, the locomotion of spinal animals can be improved by training that provides complex temporal patterns of sensory information related to stepping that is interpreted by the spinal cord. This review discusses the evidence that suggests human spinal networks can integrate and interpret complex sensory signals to produce functional efferent output and adapt to repetitive training. Locomotor training, a new rehabilitative approach, is based on principles that promote the movement of limbs and trunk to generate sensory information consistent with locomotion to improve the potential for the recovery of walking after neurologic injury.