Prevalence of allergic rhinitis comorbidity with asthma and asthma with allergic rhinitis in China: A meta-analysis
Prevalence of allergic rhinitis comorbidity with asthma and asthma with allergic rhinitis in China: A meta-analysis
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中国过敏性鼻炎合并哮喘和哮喘合并过敏性鼻炎患病率的荟萃分析
DOI：
10.12932/ap-120417-0072
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Hou-Yong Kang
中科院分区：
文献类型：
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作者：
Yang Shen;Ji-Hong Zeng;Su-Ling Hong;Hou-Yong Kang
摘要：背景：变应性鼻炎和哮喘是最常见的气道炎症性疾病。哮喘和AR之间的关系在临床上得到了广泛认可。“一个气道、一种疾病”的概念已逐渐被人们接受。然而，在中国，我们没有找到任何关于AR .伴哮喘和哮喘伴AR的患病率的系统综述和荟萃分析。目的：本研究的目的是对所有已进行研究的结果进行荟萃分析，以提供关于中国AR与哮喘以及哮喘与AR的共发率的有效信息。方法：对Pubmed/Medline、Science、Springer、Elsevier、Embase、万方数据、VIP、CBM和CNKI进行了系统检索，并由两名独立审查员从合格研究中提取数据。荟萃分析、研究质量评估和发表偏倚评估均使用Stata 12.1软件进行。结果：该荟萃分析的结果显示，AR合并哮喘的患病率估计值范围为6.69%至14.35%，哮喘合并AR的患病率估计值范围为26.67%至54%。此外，确定AR伴哮喘的总患病率为10.17%（95%CI 9.08-11.27%），哮喘伴AR的总患病率为38.97%（95%CI 34.42-43.53%）。结论：本荟萃分析首次全面定量总结了中国AR合并哮喘和哮喘合并AR的患病率。我们的研究表明，在中国，哮喘和变应性鼻炎通常是共病疾病，并在同一患者中共存。从流行病学的观点来看，AR和哮喘之间存在密切的相关性
Abstract.Background: Allergic rhinitis (AR) and asthma are the most common inflammatory diseases of the airways. The relationship between asthma and AR is widely and clinically recognised. The concept “one airway, one disease” has been .gradually accepted. However, in China, we could not find any systematic review and meta-analysis on the prevalence of AR .with asthma and asthma with AR..Objective: The aim of this research was to carry out a meta-analysis on the results of all conducted studies to present valid .information about the co-occurrence rate of AR with asthma and asthma with AR in China. .Methods: Pubmed/Medline, Science, Springer, Elsevier, Embase, Wanfang data, VIP, CBM, and CNKI were searched .systemically and data were extracted from eligible studies by two independent reviewers. Meta-analysis, study quality .assessment, and publication bias assessments were all done using Stata 12.1 software. .Results: The results of this meta-analysis showed that pooled prevalence estimates of AR with asthma ranged from 6.69% .to 14.35%, asthma with AR from 26.67% to 54%. Furthermore, an overall prevalence of 10.17% (95% CI 9.08–11.27%) was .ascertained for AR with asthma, and 38.97% (95% CI 34.42–43.53%) for asthma with AR..Conclusions: The present meta-analysis comprehensively provided the first quantitative summary of the prevalence of AR .with asthma and asthma with AR in China. Our study demonstrated that, in China, asthma and AR are often comorbid .diseases and co-exist in the same patients. There is a close correlation between AR and asthma from an epidemiological .standpoint