Responses to captopril and hydrochlorothiazide in black patients with hypertension
Responses to captopril and hydrochlorothiazide in black patients with hypertension
复制标题
黑人高血压患者对卡托普利和氢氯噻嗪的反应
DOI：
10.1038/clpt.1982.165
复制
发表时间：
1982
影响因子：
6.7
通讯作者：
J. Lunn
中科院分区：
文献类型：
--
作者：
M. Moser;J. Lunn
The effects of Captopril (C) in doses of up to 450 mg/day, placebo (P), and hydrochlorothiazide (H) in doses of 50 to 100 mg/day were compared in double‐blind studies in 38 black patients. Mean blood pressure response to C was only slightly greater than to P (systolic response difference only). Mean blood pressure responses to H were greater than to C. Results were compared to available data on 185 white and black patients treated similarly. In white patients, response to C was greater than to P, but response to H was approximately equal to that to C. In black patients, results were of the same order as those reported here; the systolic response to C was greater than that to P and the response to H was greater than that to C. These data suggest that black and white patients differ in response to certain antihypertensive drugs.
