Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay

Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay
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DOI:
10.1016/j.antiviral.2003.12.005
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发表时间:
2004-06-01
期刊:
影响因子:
7.6
通讯作者:
Wutzler, P
Wutzler, P
中科院分区:
医学2区
文献类型:
--
作者:
Friedrichs, C;Neyts, J;Wutzler, P

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A real-time quantitative PCR was developed to assess antiviral activity of molecules against human herpesvirus 8 (HHV-8) and the Epstein-Barr Virus (EBV). The antiviral activity of the reference molecules acyclovir, ganciclovir, cidofovir, adefovir and brivudin, as assessed by this methodology, proved very similar to the activity as determined by a DNA-DNA hybridisation method. (C) 2004 Published by Elsevier B.V.