Neonatal Invasive Haemophilus influenzae Disease in England and Wales: Epidemiology, Clinical Characteristics, and Outcome
Neonatal Invasive Haemophilus influenzae Disease in England and Wales: Epidemiology, Clinical Characteristics, and Outcome
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DOI：
10.1093/cid/civ194
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发表时间：
2015-06-15
影响因子：
11.8
通讯作者：
Ladhani, Shamez N.
中科院分区：
文献类型：
--
作者：
Collins, Sarah;Litt, David J.;Ladhani, Shamez N.
背景无法分型的流感嗜血杆菌（NTHi）经常引起儿童非侵入性上呼吸道感染，但也可引起侵入性疾病，主要发生在老年人中。一些研究报告了围产期侵袭性NTHi疾病的负担增加。在这里，我们描述了新生儿侵袭性H。流感疾病在英格兰和威尔士超过5年的时间。英国公共卫生部加强了对侵入性H。流感在英格兰和威尔士。获得了所有实验室确诊的婴儿病例的详细临床信息，
Background. Nontypeable Haemophilus influenzae (NTHi) frequently causes noninvasive upper respiratory tract infections in children but can cause invasive disease, mainly in older adults. An increased burden of invasive NTHi disease in the perinatal period has been reported by a number of studies. Here we describe the epidemiology, clinical characteristics, and outcome of neonatal invasive H. influenzae disease in England and Wales over a 5-year period.Methods. Public Health England conducts enhanced national surveillance of invasive H. influenzae disease in England and Wales. Detailed clinical information was obtained for all laboratory-confirmed cases in infants aged