Changes in the Swine Gut Microbiota in Response to Porcine Epidemic Diarrhea Infection.
Changes in the Swine Gut Microbiota in Response to Porcine Epidemic Diarrhea Infection.
复制标题
DOI：
10.1264/jsme2.me15046
复制
发表时间：
2015
影响因子：
2.2
通讯作者：
Park SJ
中科院分区：
文献类型：
--
作者：
Koh HW;Kim MS;Lee JS;Kim H;Park SJ
哺乳动物的胃肠道是一个复杂的生态系统，具有独特的环境，由数百种不同类型的细菌细胞组成。肠道菌群可能在宿主肠道健康中起着至关重要的作用。我们在此试图确定可能受猪流行性腹泻（PED）影响的微生物群变化。我们观察到，在门和属水平上，对照组和PED病毒（PEDV）感染组之间的微生物群存在显著差异。由于PEDV感染引起的生态失调，健康胃肠道中的大多数共生细菌（如冻杆菌、普雷沃氏菌和粪杆菌）减少。
The gastrointestinal tract of mammals is a complex ecosystem with distinct environments and comprises hundreds of different types of bacterial cells. The gut microbiota may play a critical role in the gut health of the host. We herein attempted to identify a microbiota shift that may be affected by porcine epidemic diarrhea (PED). We observed significant differences in microbiota between the control and PED virus (PEDV)-infected groups at both the phylum and genus level. Most commensal bacteria (i.e. Psychrobacter, Prevotella, and Faecalibacterium) in the healthy gastrointestinal tract were decreased due to dysbiosis induced by PEDV infection.