Molecular biology of the sea urchin embryo.
Molecular biology of the sea urchin embryo.
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海胆胚胎的分子生物学。
DOI：
10.1126/science.6178156
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Britten,RJ
中科院分区：
文献类型：
--
作者：
Davidson,EH;Hough-Evans,BR;Britten,RJ
对海胆早期发育的研究为胚胎发生过程提供了新的见解。未受精卵中储存的母体信使 RNA 支持早期胚胎中的大部分蛋白质合成，但母体转录本的结构表明还可能具有其他功能。转录和蛋白质合成的总体发育模式是已知的，当前的测量描述了特定基因的表达，包括组蛋白基因、核糖体基因和肌动蛋白基因。对于产生特定细胞谱系（例如微粒-间充质细胞谱系）的早期胚胎区域，探索了发育定型的可能机制。
Research on the early development of the sea urchin offers new insights into the process of embryogenesis. Maternal messenger RNA stored in the unfertilized egg supports most of the protein synthesis in the early embryo, but the structure of maternal transcripts suggests that additional functions are also possible. The overall developmental patterns of transcription and protein synthesis are known, and current measurements describe the expression of specific genes, including the histone genes, the ribosomal genes, and the actin genes. Possible mechanisms of developmental commitment are explored for regions of the early embryo that give rise to specified cell lineages, such as the micromere-mesenchyme cell lineage.