Could concurrent biopsy and microwave ablation be reliable? Concordance between frozen section examination and final pathology in CT-guided biopsy of lung cancer
Could concurrent biopsy and microwave ablation be reliable? Concordance between frozen section examination and final pathology in CT-guided biopsy of lung cancer
复制标题
同时进行活检和微波消融可靠吗？
DOI：
10.1080/02656736.2021.1947528
复制
发表时间：
2021-01
影响因子：
3.1
通讯作者：
Xin Ye
中科院分区：
文献类型：
--
作者：
Zhigang Wei;Xia Yang;Yan Feng;Yongmei Kong;Zhigang Yao;Jiwei Ma;Xin Ye
摘要目的微波消融联合同期活检治疗肺癌。冰冻切片诊断是最终病理学诊断的重要补充。因此，我们进行了一项回顾性研究，以评估在计算机断层扫描（CT）引导下肺癌活检中FS检查和FP之间的一致性。材料与方法回顾性研究经皮肺穿刺活检术并经术中FS检查和FP诊断的患者。FS和FP在诊断恶性肺癌和明确组织学类型方面的一致性。结果共纳入163例患者。恶性肿瘤诊断符合率为96.3%。112例患者（68.7%）FS检查和FP检查的明确组织学类型一致。在18例患者中观察到的最常见类型是未定义FS但诊断为腺癌FP的肺癌。对于需要免疫组化诊断FP的患者，组织学类型的一致性较低（47.3% vs. 79.6%，p < 0.000）。使用FP诊断的不同组织学类型的一致率不同（腺癌vs.鳞状细胞癌vs.小细胞肺癌vs.其他，76.6 vs. 56.2 vs. 69.2 vs. 0.0%，p < 0.000）。结论FS对肺癌组织学类型的诊断不如FP，但对肺癌的诊断与FP有较高的一致性。
Abstract Purpose Microwave ablation combined with concurrent biopsy has been used for lung cancer. Frozen section (FS) diagnosis is an important supplement for the final pathology (FP). Thus, a retrospective study was conducted to evaluate the concordance between FS examination and FP in the computed tomography (CT)-guided biopsy of lung cancer. Materials and methods Patients who underwent percutaneous transthoracic needle lung biopsies and were diagnosed using both intraoperative FS examination and FP were retrospectively enrolled. Concordance between FS findings and FP in the diagnosis of malignant lung cancer and the definitive histology types were recorded. Results Overall, 163 patients were enrolled. The concordance rate in the diagnosis of malignant tumors was 96.3%. The definitive histology types were concordant between FS examinations and FP in 112 patients (68.7%). Lung cancers undefined with FS but diagnosed as adenocarcinoma with FP were the most common type, observed in 18 patients. The concordance in the histology type was lower for those requiring immunohistochemistry for FP diagnoses (47.3 vs. 79.6%, p < 0.000). Concordance rates differed for the different histology types diagnosed using FP (adenocarcinoma vs. squamous cell carcinoma vs. small-cell lung cancer vs. others, 76.6 vs. 56.2 vs. 69.2 vs. 0.0%, p < 0.000). Conclusions FS was inferior to FP in the diagnosis of definitive histology types, but had a high concordance with FP in the diagnosis of malignant lung cancer.
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DOI：
10.1016/j.jtcvs.2004.07.038
发表时间：
2005-05-01
影响因子：
6
作者：
Yoshida, J;Nagai, K;Nishiwaki, Y
通讯作者：
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DOI：
10.1007/s00432-020-03176-z
发表时间：
2020-05-01
影响因子：
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影响因子：
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影响因子：
20.4
作者：
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Choe, Gheeyoung
影响因子：
1.2
作者：
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Hirono, Tatsuhiko