B cell memory: understanding COVID-19.
B cell memory: understanding COVID-19.
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DOI:
10.1016/j.immuni.2021.01.014
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发表时间:
2021-02-09
期刊:
影响因子:
32.4
通讯作者:
Tarlinton D
中科院分区:
文献类型:
--
作者:
Quast I;Tarlinton D
Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defense strategy and underlie virtually all vaccine success. Here, we explain how B cell memory is generated by infection and vaccination, what influences its efficacy and its persistence, and how characterizing these parameters in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will help achieve protective immunity through vaccination. Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defense strategy and underlie virtually all vaccine success. Here, we explain how B cell memory is generated by infection and vaccination, what influences its efficacy and its persistence, and how characterizing these parameters in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will help achieve protective immunity through vaccination.
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影响因子:
7.7
作者:
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Bieniasz PD
影响因子:
32.4
作者:
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影响因子:
64.5
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通讯作者:
Wilson PC
DOI:
10.1084/jem.20110740
发表时间:
2011-12-19
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Purtha WE;Tedder TF;Johnson S;Bhattacharya D;Diamond MS
通讯作者:
Diamond MS