Silent hypoxia: A harbinger of clinical deterioration in patients with COVID-19
Silent hypoxia: A harbinger of clinical deterioration in patients with COVID-19
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DOI：
10.1016/j.ajem.2020.05.044
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发表时间：
2020-10-01
影响因子：
3.6
通讯作者：
Brown, Robert
中科院分区：
文献类型：
--
作者：
Wilkerson, R. Gentry;Adler, Jason D.;Brown, Robert
感染SARS-CoV-2病毒的患者可能会出现各种各样的症状，包括完全无症状。尽管没有症状或症状很小，但有些患者的脉搏血氧饱和度读数可能明显降低。这被称为“沉默的”或“冷漠的”缺氧（Ottestad等人，2020 [1]）。我们报告了一例72岁男性COVID-19综合征患者，他在急诊室就诊时症状轻微，但外周血氧饱和度读数较低。患者在接下来的几天里病情恶化，最终因压倒性的多器官系统衰竭而死亡。该病例强调了外周血氧测量在评估SARS-CoV-2感染患者中的实用性。从急诊科出院的患者自我监测脉搏血氧饱和度是识别需要返回进行进一步评估的患者的潜在方法。(C)2020爱思唯尔公司All rights reserved.
Patients infected with the SARS-CoV-2 virus can present with a wide variety of symptoms including being entirely asymptomatic. Despite having no or minimal symptoms, some patients may have markedly reduced pulse oximetry readings. This has been referred to as "silent" or "apathetic" hypoxia (Ottestad et al., 2020 [1]). We present a case of a 72-year-old male with COVID-19 syndrome who presented to the emergency department with minimal symptoms but low peripheral oxygen saturation readings. The patient deteriorated over the following days and eventually died as a result of overwhelming multi-organ system failure. This case highlights the utility of peripheral oxygen measurements in the evaluation of patients with SARS-CoV-2 infection. Self-monitoring of pulse oximetry by patients discharged from the emergency department is a potential way to identify patients needing to return for further evaluation. (C) 2020 Elsevier Inc. All rights reserved.