Bayesian analysis for mixtures of discrete distributions with a non-parametric component
Bayesian analysis for mixtures of discrete distributions with a non-parametric component
复制标题
具有非参数分量的离散分布混合的贝叶斯分析
DOI:
10.1080/02664763.2015.1100594
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发表时间:
2015
影响因子:
1.5
通讯作者:
Alhaji B
中科院分区:
文献类型:
--
作者:
Alhaji B
Bayesian finite mixture modelling is a flexible parametric modelling approach for classification and density fitting. Many areas of application require distinguishing asignalfrom anoisecomponent. In practice, it is often difficult to justify a specific distribution for thesignalcomponent; therefore, thesignaldistribution is usually further modelled via a mixture of distributions. However, modelling thesignalas a mixture of distributions is computationally non-trivial due to the difficulties in justifying the exact number of components to be used and due to the label switching problem. This paper proposes the use of a non-parametric distribution to model thesignalcomponent. We consider the case of discrete data and show how this new methodology leads to more accurate parameter estimation and smaller false non-discovery rate. Moreover, it does not incur the label switching problem. We show an application of the method to data generated by ChIP-sequencing experiments.
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
Carlos E. Rodríguez;S. Walker
通讯作者:
S. Walker
影响因子:
3
作者:
Spyrou C;Stark R;Lynch AG;Tavaré S
通讯作者:
Tavaré S
影响因子:
2.2
作者:
Nobile, Agostino;Fearnside, Alastair T.
通讯作者:
Fearnside, Alastair T.