STRAIN ENERGY FUNCTION OF RED BLOOD-CELL MEMBRANES
STRAIN ENERGY FUNCTION OF RED BLOOD-CELL MEMBRANES
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DOI：
10.1016/s0006-3495(73)85983-1
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发表时间：
1973-01-01
影响因子：
3.4
通讯作者：
CHIEN, S
中科院分区：
文献类型：
--
作者：
SKALAK, R;TOZEREN, A;CHIEN, S
在文献中报道的人红细胞膜弹性模量的几个大不相同的值被合并成一个由两项组成的单一应变能函数。其中一项给出了当红细胞膜在恒定面积下变形时所观察到的小应力和低弹性模量。第二项的各向同性应力随面积的变化而增大。将应变能函数应用于红细胞在低渗溶液中的球化过程。结果表明，即使红细胞膜在细胞的所有区域都是均匀的，也可以得到一个近乎完美的球体。还探讨了有关筛分和微移液实验的结果。
The several widely different values of the elastic modulus of the human red blood cell membrane which have been reported in the literature are incorporated into a single strain energy function consisting of two terms. One term gives the small stresses and low elastic modulus which is observed when the red cell membrane is deformed at constant area. The second term contributes a large isotropic stress dependent on the change of area. The strain energy function is applied to the process of sphering of red blood cells in a hypotonic solution. It is shown that a nearly perfect sphere can result even though the red blood cell membrane is homogeneous in all areas of the cell. Results pertinent to sieving and micropipette experiments are also explored.