Identification of phospholipid platelet-activating factor (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in human amniotic fluid and urine.

Identification of phospholipid platelet-activating factor (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in human amniotic fluid and urine.
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人羊水和尿液中磷脂血小板激活因子(1-0-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱)的鉴定。

DOI:
10.1016/0006-291x(83)90430-8
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发表时间:
1983
影响因子:
3.1
通讯作者:
Johnston,JM
Johnston,JM
中科院分区:
生物学4区
文献类型:
--
作者:
Billah,MM;Johnston,JM

文献摘要

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人羊水和胎儿尿液中磷脂血小板活化因子(PAF)的存在进行了检查。PAF被检测到的脂质提取物中的一些样品的羊水中获得的妇女在劳动力,但它是无法检测到的样品前获得的羊水劳动力。通过色谱迁移率、血小板聚集和化学修饰鉴定PAF。羊水中LysoPAF的浓度也高于PAF。在新生儿和成人尿液中也发现了PAF和lysoPAF。
Human amniotic fluid and fetal urine were examined for the presence of phospholipid platelet-activating factor (PAF). PAF was detected in lipid extracts of some samples of amniotic fluid obtained from women in labor but it was undetectable in samples of amniotic fluid obtained before the onset of labor. PAF was identified by chromatographic mobility, platelet aggregation and chemical modifications. LysoPAF was also present in amniotic fluid at higher concentrations than those of PAF. Both PAF and lysoPAF were identified also in newborn and adult urine.