Item Response Theory Reveals Variability of Functional Impairment within Clinical Dementia Rating Scale Stages
Item Response Theory Reveals Variability of Functional Impairment within Clinical Dementia Rating Scale Stages
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DOI：
10.1159/000335727
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发表时间：
2011-01-01
影响因子：
2.4
通讯作者：
Doody, Rachelle S.
中科院分区：
文献类型：
--
作者：
Miller, Tyler M.;Balsis, Steve;Doody, Rachelle S.
背景/目的：研究项目反应理论(IRT)方法在临床痴呆分级(CDR)阶段中测量痴呆严重程度变化是否与日常生活能力(ADLS)有关。方法：将1181例患者CDR期痴呆严重程度的IRT估计值与ADLS进行相关分析。结果：在4个痴呆受损阶段中的3个阶段，IRT确定的痴呆严重程度与ADLS显著相关。结论：与传统的CDR评分方法相比，IRT方法显示出相当大的优势，不仅因为它提高了痴呆症测量的精确度，而且还因为它使人们能够发现与ADLS等功能结果更精确的联系。版权所有(C)2012 S.Karger AG，巴塞尔
Background/Aims: To investigate whether an item response theory (IRT) approach to measuring variations of dementia severity within Clinical Dementia Rating (CDR) stages is associated with activities of daily living (ADLs). Methods: IRT estimates of dementia severity within CDR stages in 1,181 patients were correlated with ADLs and analyzed. Results: IRT-determined dementia severity was significantly correlated with ADLs in three of four impaired dementia stages. Conclusion: An IRT approach shows considerable advantages over traditional scoring practices of the CDR not only because it increases precision in dementia measurement, but also because it enables one to discover more precise associations with functional outcomes such as ADLs. Copyright (C) 2012 S. Karger AG, Basel