An independent, landmark-dominated head-direction signal in dysgranular retrosplenial cortex.
An independent, landmark-dominated head-direction signal in dysgranular retrosplenial cortex.
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一个独立的，具有里程碑意义的头向信号，在肾上腺后皮层中。
DOI：
10.1038/nn.4465
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发表时间：
2017-02
影响因子：
25
通讯作者：
Jeffery K
中科院分区：
文献类型：
--
作者：
Jacob PY;Casali G;Spieser L;Page H;Overington D;Jeffery K
我们研究了地标如何影响大脑对头部方向的计算，发现在双向对称的环境中，颗粒异常压后皮质中的一些神经元表现出双向放电模式。这表明即使当局部环境线索与全局头部方向信号冲突时，局部环境线索也会主导神经活动。它提出了一种机制，用于根据其方向稳定性/实用性将地标与头部方向信号相关联或将其与头部方向信号分离。
We investigated how landmarks influence the brain’s computation of head direction and found that in a bi-directionally symmetrical environment, some neurons in dysgranular retrosplenial cortex showed bi-directional firing patterns. This indicates dominance of neural activity by local environmental cues even when these conflict with the global head direction signal. It suggests a mechanism for associating landmarks to or dissociating them from the head direction signal, according to their directional stability/utility.