Bipolar depression: the real challenge

Bipolar depression: the real challenge
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DOI:
10.1016/j.euroneuro.2004.03.001
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发表时间:
2004-05-01
影响因子:
5.6
通讯作者:
Hirschfeld, RMA
Hirschfeld, RMA
中科院分区:
医学2区
文献类型:
--
作者:
Hirschfeld, RMA

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本文旨在提高对双相抑郁症的影响和负担的认识,以及在临床实践中提高其认识和管理的必要性。双相抑郁症通常被误诊为单相抑郁症,因此,患者可能会接受不适当的治疗,可能会使症状恶化。心境障碍问卷(MDQ)是一个有用的筛选工具,用于确定双相谱系障碍的范围在一般和精神病人群。双相抑郁症对患者的影响很大,影响工作、社交活动、家庭和朋友。目前对双相情感障碍的治疗主要集中在躁狂症,但双相抑郁症的症状发生更频繁,持续时间更长,更具破坏性,并且与躁狂症相比自杀风险更大。与单相抑郁症相比,双相抑郁症更严重,与更频繁的医院就诊相关,并导致更大的心理社会损害。这些事实强调了改善双相抑郁症诊断和治疗的重要性。(C)2004年由Elsevier B.V/ECNP出版。
This paper seeks to raise awareness of the impact and burden of bipolar depression and the need to improve its recognition and management in clinical practice. Bipolar depression is commonly misdiagnosed as unipolar depression and consequently, patients may receive inappropriate treatment that could potentially worsen symptoms. The Mood Disorder Questionnaire (MDQ) is a useful screening tool for identifying the range of bipolar spectrum disorders in general and psychiatric populations. Bipolar depression has a significant impact on patients, affecting work, social activities, family and friends. Current treatments for bipolar disorder have focused on mania, yet symptoms of bipolar depression occur more frequently, last longer, are more disruptive and are associated with greater risk of suicide than mania. In comparison with unipolar depression, bipolar depression is more severe, is associated with more frequent hospital visits and causes greater psychosocial impairment. These facts emphasise the importance of improving the diagnosis and treatment of bipolar depression. (C) 2004 Published by Elsevier B.V/ECNP.