Other chemical constituents isolated from Solanum crinitum Lam. (Solanaceae)
Other chemical constituents isolated from Solanum crinitum Lam. (Solanaceae)
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DOI：
10.1590/s0103-50532010001200007
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发表时间：
2010-12-01
影响因子：
1.4
通讯作者：
Braz-Filho, Raimundo
中科院分区：
文献类型：
--
作者：
Cornelius, Marli T. F.;Carvalho, Mário G. de;Braz-Filho, Raimundo
通过植物化学研究，从荆芥果实的毛状体中分离出四种黄酮类化合物，即铁力苷(1)、黄芪苷(2)、山奈酚(3)、生物茶素a- 7- o - β - d -apiofuranosyl-(1 -> - 5)- β - d -apiofuranosyl-(1 -> - 6)- β - d -葡萄糖吡喃苷(7)、4-羟基苯甲酸（12）和四种肉桂酸衍生物，顺式和反式香豆酸（10和11）、顺式和反式香豆酸乙酯（8和9）。从青果甲醇提取物中分离得到3种三糖基甾体生物碱，分别为太阳碱（13）、20-外延太阳碱（14）和太阳碱（16）。合成了衍生物3,5,7,4'-曲- o -甲基山奈酚(4)、3,7,4'-三- o -甲基山奈酚(5)、3,7,4'-三- o -甲基-5- o -乙酰山奈酚(6)、过乙酰-外延太阳精（15）和过乙酰-太阳碱（17）。通过分析它们的光谱数据，确定了它们的结构。对这些生物碱的过乙酰基衍生物进行了完整的H-1和C-13核磁共振配位。
The phytochemical investigation of Solanum crinitum Lam led to the isolation from the fruit trichomes of four flavonoids, tiliroside (1), astragalin (2), kaempferol (3), biochanin A-7-O-beta-D-apiofuranosyl-(1 -> 5)-beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranoside (7), along with 4-hydroxybenzoic acid (12), and four cinnamic acid derivatives, cis- and trans-coumaric acids (10 and 11) and cis- and trans- ethyl coumarate (8 and 9). Three tri-glycosyl-steroidal alkaloids, solamargine (13), 20-epi-solamargine (14) and solasonine (16) were isolated from the methanolic extract of the green fruits. The derivatives 3,5,7,4'-tretra-O-methyl-kaempferol (4), 3,7,4'-tri-O-methyl-kaempferol (5), 3,7,4'-tri-O-methyl-5-O-acetyl-kaempferol (6), the peracetyl-epi-solamargine (15) and peracetyl-solasonine (17) were prepared. The structures were established through the analysis of their spectral data. The complete H-1 and C-13 NMR data assignments of the new peracetyl derivatives of the alkaloids were made.