THE ELASTIC-MODULI OF HUMAN SUBCHONDRAL, TRABECULAR, AND CORTICAL BONE TISSUE AND THE SIZE-DEPENDENCY OF CORTICAL BONE MODULUS
THE ELASTIC-MODULI OF HUMAN SUBCHONDRAL, TRABECULAR, AND CORTICAL BONE TISSUE AND THE SIZE-DEPENDENCY OF CORTICAL BONE MODULUS
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DOI：
10.1016/0021-9290(90)90003-l
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发表时间：
1990-01-01
影响因子：
2.4
通讯作者：
GOLDSTEIN, SA
中科院分区：
文献类型：
--
作者：
CHOI, K;KUHN, JL;GOLDSTEIN, SA
通过三点弯曲实验，在微观结构水平上测定了人胫骨近端软骨下骨、骨小梁和皮质骨的弹性模量。软骨下标本的平均模数为1.15 GPa，骨小梁和皮质标本的平均模数分别为4.59 GPa和5.44 GPa。骨组织间的模量值存在显著差异，这可能主要是由于各骨组织微结构的差异，而不是骨密度的差异。此外，使用8种不同大小的皮质标本(高度h=100-1000µm)来检验弹性系数的尺寸依赖关系。虽然相对较大的样品(h>；500µm)的模量值保持相当恒定(约15 Gpa)，但随着样品变小，该值降低。发现弹性模数与试件尺寸之间存在显著的相关性。表面积与体积的比率被证明是解释这种尺寸依赖关系的关键变量。
The elastic moduli of human subchondral, trabecular, and cortical bone tissue from a proximal tibia were experimentally determined using three-point bending tests on a microstructural level. The mean modulus of subchondral specimens was 1.15 GPa, and those of trabecular and cortical specimens was 4.59 GPa and 5.44 GPa respectively. Significant differences were found in the modulus values between bone tissues, which may have mainly resulted from the differences in the microstructures of each bone tissue rather than in the mineral density. Furthermore, the size-dependency of the modulus was examined using eight different sizes of cortical specimens (heights h=100-1000 .mu.m). While the modulus values for relatively large specimens (h>500 .mu.m) remained fairly constant (approximately 15 GPa), the values decreased as the specimens became smaller. A significant correlation was found between the modulus and specimen size. The surface area to volume ratio proved to be a key variable to explain the size-dependency.