Mechanisms of auxin signaling

Mechanisms of auxin signaling
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DOI:
10.1242/dev.131870
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发表时间:
2016-09-15
期刊:
影响因子:
4.6
通讯作者:
Estelle, Mark
Estelle, Mark
中科院分区:
生物学2区
文献类型:
--
作者:
Lavy, Meirav;Estelle, Mark

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植物激素生长素触发复杂的生长和发育过程。其潜在的分子作用机制通过生长素依赖的转录抑制因子降解促进转录抑制和基因激活之间的快速切换。核生长素信号通路由少量核心组分组成。然而,在大多数植物中,每个组分都由一个大的基因家族代表。因此,该途径的模块化结构可以根据细胞和环境背景产生不同的转录产物。在这里,并在所附的海报,我们概述了目前的模型TIR 1/黄曲霉毒素B依赖的生长素信号,重点是最近的研究。
The plant hormone auxin triggers complex growth and developmental processes. Its underlying molecular mechanism of action facilitates rapid switching between transcriptional repression and gene activation through the auxin-dependent degradation of transcriptional repressors. The nuclear auxin signaling pathway consists of a small number of core components. However, in most plants each component is represented by a large gene family. The modular construction of the pathway can thus produce diverse transcriptional outputs depending on the cellular and environmental context. Here, and in the accompanying poster, we outline the current model for TIR1/AFB-dependent auxin signaling with an emphasis on recent studies.