Diffusion Tensor Tractography in the Head-and-Neck Region Using a Clinical 3-T MR Scanner
Diffusion Tensor Tractography in the Head-and-Neck Region Using a Clinical 3-T MR Scanner
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DOI：
10.1016/j.acra.2009.01.019
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发表时间：
2009-07-01
影响因子：
4.8
通讯作者：
Yamashita, Yasuyuki
中科院分区：
文献类型：
--
作者：
Akter, Masuma;Hirai, Toshinori;Yamashita, Yasuyuki
理由和目标。在3 T条件下对头颈部神经纤维进行弥散张量纤维束成像（DTT）尚未见报道。本研究的目的是评估的可行性，使用DTT的可视化神经纤维在头颈部地区在3 T，并探讨使用这种方法在头颈部肿块病变的患者。使用3 T扫描仪，我们获得了头部和颈部区域的磁共振图像：5名健康志愿者和5例头颈部肿块病变患者。所有受试者均接受了解剖T1加权和弥散张量成像，使用的序列具有6个运动探测梯度方向，B值为800秒/mm（2），像素矩阵为128 x 128。纤维跟踪采用连续跟踪法。不同的后处理参数进行了研究，以优化纤维密度检测和最小化噪声。在5例头颈部肿块性病变中，两名研究者还将纤维束造影结果与手术所见进行了关于肿块和神经关系的比较。采用双感兴趣区法，在最大角度40 °和最小纤维长度10 mm处描绘了假定的下牙槽神经的最大纤维密度。5例患者均成功描绘了DTT。4例DTT与手术结果一致或相似。观察者之间的一致性良好。结论。应用临床3 T磁共振扫描仪对头颈部神经纤维进行DTT检查是可行的。来自少数头颈部病变患者的数据显示纤维束成像与手术结果之间具有良好的一致性。
Rationale and Objectives. Diffusion tensor tractography (DTT) for neural fibers of the head-and-neck region at 3T has not been reported. The purpose of this study was to evaluate the feasibility of using DTT for visualizing neural fibers in the head-and-neck region at 3T and to explore the use of this method in patients with head-and-neck mass lesions.Materials and Methods. Using a 3T scanner, we obtained magnetic resonance images of the head and neck region in:5 healthy volunteers and 5 patients with head and neck mass lesions. All subjects underwent anatomic T1-weighted and diffusion-tensor imaging using a sequence with six motion-probing gradient orientations, a b value of 800 second/mm(2), and a 128 x 128 pixel matrix. Fiber tracking was with the continuous tracking method. Different postprocessing parameters were investigated to optimize fiber density detection and minimize noise. In five patients with head-and-neck mass lesions, comparison of tractography results and operative findings with regards to mass and nerve relationship was also performed by two observers.Results. Using the two regions-of-interest method, the greatest fiber density of presumed inferior alveolar nerves was depicted at a maximum angle of 40 degrees and a minimum fiber length of 10 mm. DTT was successfully depicted in all 5 patients. In 4 patients, the relationship between DTT and operative findings was coincided or similar. The interobserver agreement was good.Conclusions. DTT of the neural fibers in the head and neck region is feasible using a clinical 3T magnetic resonance scanner. Data from a small number of patients with head-and-neck lesions show good agreement between tractography and operative results.