Physical Activity During Daily Life and Functional Decline in Peripheral Arterial Disease
Physical Activity During Daily Life and Functional Decline in Peripheral Arterial Disease
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DOI：
10.1161/circulationaha.108.791491
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发表时间：
2009-01-20
期刊：
影响因子：
37.8
通讯作者：
McDermott, Mary M.
中科院分区：
文献类型：
--
作者：
Garg, Parveen K.;Liu, Kiang;McDermott, Mary M.
背景——很少有可改变的行为被发现与下肢外周动脉疾病患者功能衰退速度较慢有关。我们确定了日常生活中较高水平的体力活动是否与外周动脉疾病患者的功能下降较少相关。方法和结果——研究人群包括 203 名外周动脉疾病参与者，他们连续 7 天接受垂直加速度计测量的体力活动，并每年随访长达 4 年（平均 33.6 个月）。结果是 6 分钟步行表现、正常节奏和快节奏 4 米步行速度以及短期表现身体电池的年平均变化。根据年龄、性别、种族、合并症、体重指数、踝肱指数、吸烟和步行运动频率对分析进行调整。通过垂直加速度计测量的基线身体活动水平越高，6 分钟步行表现（趋势 P = 0.010）、快节奏 4 米步行速度（趋势 P = 0.002）和短期表现体力电池（趋势 P = 0.001）的年均下降显着减少相关。与基线最低四分位数相比，体力活动基线最高四分位数的人在 6 分钟步行表现（-50.82 与 -107.0 英尺/年；P=0.019）、快节奏 4 米步行速度（-0.0034 与 -0.111 m . s(-1) . y (-)1；P = 0.002）和短期体能表现方面的年下降幅度较小。电池（-0.074 对比 -0.829；P=0.005）。 结论：日常生活中较高的体力活动水平与外周动脉疾病患者的功能衰退较少相关。这些发现对于大量无法参加监督步行锻炼计划的外周动脉疾病患者来说可能特别重要。 （流通。2009 年；119：251-260。）
Background-Few modifiable behaviors have been identified that are associated with slower rates of functional decline in persons with lower-extremity peripheral arterial disease. We determined whether higher levels of physical activity during daily life are associated with less functional decline in persons with peripheral arterial disease.Methods and Results-The study population included 203 peripheral arterial disease participants who underwent vertical accelerometer-measured physical activity continuously over 7 days and were followed up annually for up to 4 years (mean, 33.6 months). Outcomes were average annual changes in 6-minute walk performance, usual-paced and fast-paced 4-m walking velocity, and the short performance physical battery. Analyses were adjusted for age, sex, race, comorbidities, body mass index, ankle brachial index, smoking, and walking exercise frequency. Higher baseline physical activity levels measured by a vertical accelerometer were associated with significantly less average annual decline in 6-minute walk performance (P for trend=0.010), fast-paced 4-m walking velocity (P for trend=0.002), and the short performance physical battery (P for trend=0.001). Compared with the lowest baseline quartile, those in the highest baseline quartile of physical activity had less annual decline in 6-minute walk performance (-50.82 versus -107.0 ft/y; P=0.019), fast-paced 4-m walking speed (-0.0034 versus -0.111 m . s(-1) . y (-)1; P = 0.002), and the short performance physical battery (-0.074 versus -0.829; P=0.005).Conclusions-Higher physical activity levels during daily life are associated with less functional decline among people with peripheral arterial disease. These findings may be particularly important for the large number of peripheral arterial disease persons without access to supervised walking exercise programs. (Circulation. 2009;119:251-260.)