Molecular composite knots
Molecular composite knots
复制标题
DOI：
10.1021/ja961459p
复制
发表时间：
1996-09-25
影响因子：
15
通讯作者：
Sauvage, JP
中科院分区：
文献类型：
--
作者：
Carina, RF;DietrichBuchecker, C;Sauvage, JP
以过渡金属组装的前驱体为原料，通过激光乙炔偶联反应制备了分子复合结。模板金属为铜(I)，纳入最终结构的配位片段为1,10-菲咯啉型螯合物。这些化合物是复合结，而不是主要结，如经典的三叶草结。通过在环二聚化反应中结合两个束缚的开链片段，得到了两种拓扑非对映体的混合物，即最简单的复合结。用来表示平面上分子的交叉点的最小数目是6个。由于纠缠前体的复杂性和几种环化可能性，复合结的形成率只有适度的（类似于3%）。另一方面，通过ES-MS（分子量4037.8）和H-1 NMR（包括二维NMR (NOESY)）对化合物进行了全面表征。
Molecular composite knots have been prepared from transition metal-assembled precursors via a Glaser acetylenic coupling reaction. The templating metal is copper(I), and the coordinating fragments incorporated into the final structure are 1,10-phenanthroline-type chelates. The compounds are composite knots as opposed to prime knots such as the classical trefoil knot. By combining two tied open-chain fragments in a cyclodimerization reaction, the simplest composite knots are obtained as a mixture of two topological diastereomers. The minimum number of crossing points used to represent the molecules in a plane is six. Due to the complexity of the entangled precursors and to the several cyclization possibilities, the formation yield of composite knots is only modest (similar to 3%). On the other hand, the compound has been fully characterized by ES-MS (molecular weight, 4037.8) and by H-1 NMR spectroscopy, including 2D NMR (NOESY).