Informatics for Chemistry, Biology, and Biomedical Sciences
Informatics for Chemistry, Biology, and Biomedical Sciences
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DOI：
10.1021/acs.jcim.0c01301
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发表时间：
2021-01-25
影响因子：
5.6
通讯作者：
Medina-Franco, Jose L.
中科院分区：
文献类型：
--
作者：
Lopez-Lopez, Edgar;Bajorath, Juergen;Medina-Franco, Jose L.
信息学正在跨学科发展，影响了化学，生物学和生物医学科学的几个领域。除了成熟的生物信息学学科外，其他基于信息学的跨学科领域也随着时间的推移而发展，例如化学信息学和生物医学信息学。其他相关的研究领域，如药物信息学，食品信息学，表观信息学，材料信息学和神经信息学最近出现，并继续发展为独立的子学科。这些学科中的每一个的目标和影响通常在文献中单独审查。因此，确定共同点和主要差异仍然具有挑战性。在此，我们讨论的背景下，在自然科学和生命科学的三个主要信息学学科，包括生物信息学，化学信息学，生物医学信息学和简要评论相关的子学科。我们集中讨论的定义，历史背景，实际影响，主要的相似之处，和差异，并评估生物信息学，化学信息学和生物医学信息学的传播和教学。
Informatics is growing across disciplines, impacting several areas of chemistry, biology, and biomedical sciences. Besides the well-established bioinformatics discipline, other informatics-based interdisciplinary fields have been evolving over time, such as chemoinformatics and biomedical informatics. Other related research areas such as pharmacoinformatics, food informatics, epi-informatics, materials informatics, and neuroinformatics have emerged more recently and continue to develop as independent subdisciplines. The goals and impacts of each of these disciplines have typically been separately reviewed in the literature. Hence, it remains challenging to identify commonalities and key differences. Herein, we discuss in context three major informatics disciplines in the natural and life sciences including bioinformatics, chemoinformatics, and biomedical informatics and briefly comment on related subdisciplines. We focus the discussion on the definitions, historical background, actual impact, main similarities, and differences and evaluate the dissemination and teaching of bioinformatics, chemoinformatics, and biomedical informatics.