Is cancer-related fatigue more strongly correlated to haematological or to psychological factors in cancer patients?
Is cancer-related fatigue more strongly correlated to haematological or to psychological factors in cancer patients?
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DOI：
10.1007/s00520-007-0357-1
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发表时间：
2008-08-01
影响因子：
3.1
通讯作者：
Mattioli, V.
中科院分区：
文献类型：
--
作者：
Romito, F.;Montanaro, R.;Mattioli, V.
工作目标癌症相关疲劳是癌症中非常常见的问题，干扰了许多患者的生活活动。大量疲惫不堪的病人会出现贫血。这项研究的目的是评估癌症相关性疲劳与血红蛋白水平以及焦虑和抑郁的存在之间的关系。材料和方法使用慢性病治疗功能评估-疲劳量表来评估疲劳。采用医院焦虑抑郁量表进行心理筛查。血液学指标通过验血进行测定。所有资料均采用卡方检验，并进行Logistic回归分析。疲劳与抑郁、疲劳与焦虑、疲劳与血红蛋白之间存在显著的相关性。结论除血红蛋白水平外，焦虑和抑郁与疲劳有关。因此，对疲劳的多维治疗的含义进行了讨论。
Goals of work Cancer-related fatigue is a very frequent problem in cancer, interfering with many patients' life activities. Anaemia is present in a large number of fatigued patients. The aim of this study was to evaluate cancer-related fatigue, in relation with haematic haemoglobin levels and the presence of anxiety and depression.Materials and methods The Functional Assessment Of Chronic Illness Therapy-Fatigue scale was used to assess fatigue. The Hospital Anxiety and Depression Scale was administered to screen for psychological distress. Haematological values were measured by blood tests. All data were analysed using Chi-squared, and a logistic regression analysis was conducted.Main results Eighty patients were enrolled in the study. Significant associations were found between fatigue and depression, fatigue and anxiety and between fatigue and haemoglobin.Conclusion Anxiety and depression, other than heamoglobin levels, were found associated with fatigue. Hence, implications for a multi-dimensional treatment of fatigue are discussed.