Actin filament dynamics in cell motility.
Actin filament dynamics in cell motility.
复制标题
细胞运动中的肌动蛋白丝动力学。
DOI：
10.1007/978-1-4615-2578-3_13
复制
发表时间：
1994
影响因子：
--
通讯作者：
Theriot,JA
中科院分区：
文献类型：
--
作者：
Theriot,JA
单个动物细胞的运动性对于许多基本的生物学过程是重要的，包括胚胎发育期间的重排、轴突生长、伤口愈合、炎症和癌症转移。动物细胞中的肌动蛋白细胞骨架也必须以依赖于细胞周期的方式急剧重排，才能进行胞质分裂。肌动蛋白微丝动力学与所有这些常见类型的细胞运动密切相关，但力传递和运动的机制仍然知之甚少。
The motility of individual animal cells is important for a wide variety of basic biological processes including rearrangements during embryonic development, neurite outgrowth, wound healing, inflammation, and cancer metastasis. The actin cytoskeleton in animal cells must also drastically rearrange in a cell-cycle dependent manner in order to perform cytokinesis. Actin microfilament dynamics are intimately involved in all of these common types of cell motility, but the mechanisms of force transduction and movement are still poorly understood.