NUMERICAL MODELING AND SIMULATION ON THE SWALLOWING OF JELLY
NUMERICAL MODELING AND SIMULATION ON THE SWALLOWING OF JELLY
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DOI：
10.1111/j.1745-4603.2009.00189.x
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发表时间：
2009-08
影响因子：
3.2
通讯作者：
H. Mizunuma;M. Sonomura;K. Shimokasa;H. Ogoshi;S. Nakamura;N. Tayama
中科院分区：
文献类型：
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作者：
H. Mizunuma;M. Sonomura;K. Shimokasa;H. Ogoshi;S. Nakamura;N. Tayama
摘要吞咽过程的研究对于吞咽困难护理食品的开发尤为重要。然而，由于仪器分辨率、对受试者的压力和误吸风险，对人类受试者进行实验的有效性在一定程度上受到限制。这些问题可能会得到解决，如果吞咽的数值模拟可以作为一种替代的调查工具。在此基础上，提出了一个数值模型来模拟吞咽一个简单的果冻丸。咽部结构采用有限元方法建模，吞咽运动由咽后壁移位、喉抬高和会厌后屈来定义。采用振荡流变仪和压缩试验研究了果冻的流变特性。一个麦克斯韦三元件模型应用到果冻的流变模型。模型常数是从压缩试验中获得的，因为压缩试验的变形模式和应力水平与吞咽果冻的变形模式和应力水平相似。器官和果冻之间的摩擦关系估计实验从果冻和湿斜面之间的摩擦测量。软果冻和硬果冻的模拟结果显示了不同的吞咽模式，这取决于它们的硬度，软果冻由于其灵活性而产生更快的吞咽。实际应用-本研究的目的是开发吞咽的数值模拟模型。数值建模适用于吞咽过程的定量分析，并且还可以预期能够对安全的护理食品进行系统研究，并为患有吞咽障碍的患者提供一定程度的舒适度。计算机模拟可用于评估，对患者无危险风险。
ABSTRACT Studies of the swallowing process are especially important for the development of care foods for dysphagia. However, the effectiveness of experiments on human subjects is somewhat limited due to instrument resolution, stress to the subjects and the risk of aspiration. These problems may be resolved if numerical simulation of swallowing can be used as an alternative investigative tool. On this basis, a numerical model is proposed to simulate the swallowing of a simple jelly bolus. The structure of the pharynx was modeled using a finite element method, and the swallowing movements were defined by pharynx posterior wall shift, laryngeal elevation and epiglottis retroflexion. The rheological characteristics of the jelly were investigated using an oscillatory rheometer and a compression test. A Maxwell three-element model was applied to the rheological model of the jelly. The model constants were obtained from compression tests because the mode of deformation and the stress level of the compression tests were similar to those of the swallowed jelly. The frictional relationship between the organs and the jelly was estimated experimentally from some frictional measurements between the jelly and a wet sloping surface. The results of the simulations for the soft and hard jellies showed different patterns of swallowing that depended on their hardness, and the soft jelly produced faster swallowing because of its flexibility. PRACTICAL APPLICATIONS The object of this study is to develop a numerical simulation model of swallowing. Numerical modeling is suitable for the quantitative analysis of the swallowing process and may also be expected to enable a systematic study of care foods that are safe and offer some degree of comfort to patients suffering from swallowing disorders. The computer simulation can be used for evaluation without dangerous risks to the patient.