Altered emotional recognition and expression in patients with Parkinson's disease.
Altered emotional recognition and expression in patients with Parkinson's disease.
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DOI：
10.2147/ndt.s149227
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发表时间：
2017
影响因子：
3.2
通讯作者：
Yu X
中科院分区：
文献类型：
--
作者：
Jin Y;Mao Z;Ling Z;Xu X;Zhang Z;Yu X
帕金森病（PD）患者表现出情绪识别和表达能力的缺陷，包括情绪化的面孔和声音。本研究旨在探讨深度脑刺激（dbs）前PD患者在视觉和听觉两种感觉模式下的情绪加工。15名需要DBS手术的PD患者和15名年龄和性别匹配的健康对照者被招募为参与者。所有参与者都接受了卡罗林斯卡定向情感面孔数据库的50张面孔识别测试。通过蒙特利尔情感声音数据库50个声音识别测试来评估声音识别。对于情绪面部表情，参与者被要求模仿五种基本情绪（中性、快乐、愤怒、恐惧和悲伤）。受试者被要求表达五种基本情绪的非语言表达。招募了15名母语为汉语的人作为解码器。我们记录了回答的准确性、反应时间和置信度。在情绪识别和表达方面，PD组在面部和声音情绪处理方面的得分低于健康对照组。两组在反应时间和信心水平上均有显著差异。当考虑到两组之间的所有参与者时，情绪识别和情绪表达之间也存在显著的关系。PD组在识别和表达任务上表现较差。面部情绪缺陷和声音情绪异常相互关联。此外，我们的数据让我们推测，情感识别和表达可能共享一个共同的系统。
Parkinson’s disease (PD) patients exhibit deficits in emotional recognition and expression abilities, including emotional faces and voices. The aim of this study was to explore emotional processing in pre-deep brain stimulation (pre-DBS) PD patients using two sensory modalities (visual and auditory). Fifteen PD patients who needed DBS surgery and 15 healthy, age- and gender-matched controls were recruited as participants. All participants were assessed by the Karolinska Directed Emotional Faces database 50 Faces Recognition test. Vocal recognition was evaluated by the Montreal Affective Voices database 50 Voices Recognition test. For emotional facial expression, the participants were asked to imitate five basic emotions (neutral, happiness, anger, fear, and sadness). The subjects were required to express nonverbal vocalizations of the five basic emotions. Fifteen Chinese native speakers were recruited as decoders. We recorded the accuracy of the responses, reaction time, and confidence level. For emotional recognition and expression, the PD group scored lower on both facial and vocal emotional processing than did the healthy control group. There were significant differences between the two groups in both reaction time and confidence level. A significant relationship was also found between emotional recognition and emotional expression when considering all participants between the two groups together. The PD group exhibited poorer performance on both the recognition and expression tasks. Facial emotion deficits and vocal emotion abnormalities were associated with each other. In addition, our data allow us to speculate that emotional recognition and expression may share a common system.