A fifty year mortality follow-up study of veterans exposed to low level chemical warfare agent, mustard gas
A fifty year mortality follow-up study of veterans exposed to low level chemical warfare agent, mustard gas
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DOI：
10.1016/s1047-2797(00)00060-0
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发表时间：
2000-07-01
影响因子：
5.6
通讯作者：
Kang, H
中科院分区：
文献类型：
--
作者：
Bullman, T;Kang, H
目得：为了确定是否有一个增加的风险与低水平芥子气暴露的任何原因特定的死亡率之间的第二次世界大战海军veterinary.METHODS：一个回顾性死亡率随访研究进行了比较的死亡率的第二次世界大战海军退伍军人谁收到低水平的非致命性芥子气暴露的第二次世界大战海军退伍军人谁没有暴露。这项研究确定了1545名海军新兵驻扎在班布里奇，马里兰州，1944年至1945年之间，谁自愿参加芥子气室测试。这些退伍军人在穿着防护服和戴着面具时暴露在芥子气中。对照组退伍军人由2663名海军退伍军人组成，他们与暴露者在相同的地点和时间服役，但没有参加室内试验。使用调整和未调整的相对风险estimations.RESULTS：在接受室内试验的海军退伍军人中，与芥子气暴露和芥子气暴露水平相关的原因特异性死亡率风险没有超过任何原因特异性死亡率。结论：第二次世界大战退伍军人所经历的芥子气暴露水平足以引起皮肤反应（红斑、水疱和溃疡）与任何原因特异性死亡风险增加无关。Ann Epidemiol 2000;10：333-338.出版社：Elsevier Science Inc.
PURPOSE: To determine if there is an increased risk of any cause specific mortality associated with low level mustard gas exposure among World War II Navy veterans.METHODS: A retrospective mortality follow-up study was conducted comparing the mortality of World War II Navy veterans who received low-level non-lethal exposures of mustard gas to that of World War II Navy veterans who were not exposed. This study identified 1545 Navy recruits stationed at Bainbridge, Maryland, between 1944-1945, who voluntarily participated in mustard gas chamber tests. These Veterans were exposed to mustard gas while wearing protective clothing and masks. Control veterans consisted of 2663 Navy veterans who served at the same location and time as the exposed, bur did not participate in chamber tests. Cause specific mortality risks associated with mustard gas exposure and level of mustard gas exposure were examined using adjusted and unadjusted relative risk estimates.RESULTS: There was no excess of any cause specific mortality associated with varying levels of mustard gas exposures among Navy veterans subject to the chamber tests.CONCLUSIONS: The levels of mustard gas exposures experienced by World War II veterans, which were sufficient to cause skin reactions (erythema, vesicles, and ulceration), were not associated with any increased risk of cause specific mortality. Ann Epidemiol 2000;10:333-338. Published by Elsevier Science Inc.