Pleuroparenchymal fibroelastosis in patients with pulmonary disease secondary to bone marrow transplantation
Pleuroparenchymal fibroelastosis in patients with pulmonary disease secondary to bone marrow transplantation
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DOI：
10.1038/modpathol.2011.114
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发表时间：
2011-12-01
期刊：
影响因子：
7.5
通讯作者：
Nicholson, Andrew G.
中科院分区：
文献类型：
--
作者：
von der Thuesen, Jan H.;Hansell, David M.;Nicholson, Andrew G.
本研究介绍了4例接受骨髓移植后发生胸膜实质弹力纤维增生症的患者，迄今为止报告为特发性疾病。在高分辨率计算机断层扫描上，所有患者的临床表现均为气胸和胸膜下纤维化。除了预期的闭塞性细支气管炎外，组织病理学还显示共存的胸膜下变化，并讨论了骨髓移植后肺部疾病中多个解剖区室的病理关系。现代病理学（2011）24，1633-1639; doi：10.1038/modpathol.2011.114; 2011年8月5日在线发表
This study presents four patients who underwent bone marrow transplantation and subsequently developed pleuroparenchymal fibroelastosis, hitherto reported as an idiopathic condition. All presented clinically with pneumothorax and subpleural fibrosis on high-resolution computed tomography. In addition to the expected obliterative bronchiolitis, histopathology showed coexistent subpleural changes, and the relationship of pathology in multiple anatomic compartments in post bone marrow transplantation pulmonary disease is discussed. Modern Pathology (2011) 24, 1633-1639; doi:10.1038/modpathol.2011.114; published online 5 August 2011