Alcohol and Drug Use and Aberrant Drug-Related Behavior Among Patients on Chronic Opioid Therapy.
Alcohol and Drug Use and Aberrant Drug-Related Behavior Among Patients on Chronic Opioid Therapy.
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DOI：
10.1080/10826084.2016.1276189
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发表时间：
2017-08-24
影响因子：
2
通讯作者：
Weisner C
中科院分区：
文献类型：
--
作者：
Campbell CI;Kline-Simon AH;Von Korff M;Saunders KW;Weisner C
To better identify individuals on chronic opioid therapy (COT) at high risk for aberrant-drug related behavior (ADRB). We examine whether patients with low level alcohol and drug use have similar characteristics to those with alcohol and drug disorders. We then examined the relationship of alcohol and drug use to ADRBs among COT patients. The sample was 972 randomly selected COT patients (age 21–80 years old) from a large health system in Northern California, USA, and interviewed in 2009. Logistic regression models were used to model the dependent variables of: alcohol use, illicit drug use, alcohol disorders, illicit drug disorders, and ADRBs. The odds of daily/weekly alcohol use were lower for those with a high daily opioid dose (120 + mg/day vs. <20 mg/day) (OR = 0.32, p < 0.010). Illicit drug disorders were associated with depression (OR = 2.31, p < .001) and being on a high daily opioid dose (OR = 5.51, p < .01). Participants with illicit drug use had higher odds of giving (OR = 2.57, p < 0.01) and receiving opioids from friends or family (OR = 3.25, p < 0.001), but disorder diagnoses were not associated with ADRBs. Findings reinforce that illicit drug use should be of high concern to clinicians prescribing opioids, and suggest it should be considered separately from alcohol use and alcohol disorders in the evaluation of ADRBs. Frequent alcohol use is low, but not uncommon, and suggests a need to discuss specific issues regarding safe use of opioids among persons who use alcohol that may differ from their risk of drug use.
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影响因子：
--
作者：
Braden, Jennifer Brennan;Russo, Joan;Sullivan, Mark D.
通讯作者：
Sullivan, Mark D.
影响因子：
120.7
作者：
Hall, Aron J.;Logan, Joseph E.;Paulozzi, Leonard J.
通讯作者：
Paulozzi, Leonard J.
影响因子：
4.4
作者：
Mars, Sarah G.;Bourgois, Philippe;Ciccarone, Daniel
通讯作者：
Ciccarone, Daniel
影响因子：
39.2
作者：
Dunn, Kate M.;Saunders, Kathleen W.;Von Korff, Michael
通讯作者：
Von Korff, Michael
据报道，终身异常吸毒行为可预测初级保健患者当前的药物使用和心理健康问题。
DOI：
10.1111/j.1526-4637.2008.00491.x
发表时间：
2008-11
期刊：
Pain medicine (Malden, Mass.)
影响因子：
--
作者：
Fleming MF;Davis J;Passik SD
通讯作者：
Passik SD