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Redefining the phenotype in complex diseases through latent classes to model intra- and inter-family heterogeneity: application to genetic linkage and association analysis.

Redefining the phenotype in complex diseases through latent classes to model intra- and inter-family heterogeneity: application to genetic linkage and association analysis.
通过潜在类别重新定义复杂疾病的表型以模拟科内和科间异质性：应用于遗传连锁和关联分析。
批准号：
172420
负责人：
Labbe Aurelie
金额：
$13.5万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-09-01 至 2011-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=172420&lang=en
关键词：
Gene Expression Data Genetic Basis Of Complex Diseases Genetic Heterogeneity Genetic Linkage Analysis Latent Class Analysis Multivariate Phenotypes

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中文摘要
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英文摘要
Identifying the genes involved in complex diseases such as cardio-vascular disease, diabetes, asthma and psychiatric disorders is a challenge in Human genetics. The task is difficult because what we see as one disease is often a collection of several dise
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Redefining the phenotype in complex diseases through latent classes to model intra- and inter-family heterogeneity: application to genetic linkage and association analysis.
  • 批准号：
    191820
  • 项目类别：
    Operating Grants
  • 资助金额：
    $2.19万
  • 财政年份：
    2009
  • 负责人：
    Labbe Aurelie
  • 依托单位：
    McGill University