CD9 and its partners: their role in induction of mitotic catastrophe and in irradiation and microtubule-targeted drug sensitivity.

CD9 及其伙伴：它们在诱导有丝分裂灾难以及辐射和微管靶向药物敏感性中的作用。

• 批准号: 171231
• 负责人: Chevrette Mario
• 金额: $ 22.81万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2011-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=171231&lang=en
• 关键词: Cd9; Microtubule-Targeted Drugs Sensitivity; Mitotic Catastrophe And Mitotic Cell Death; Prostate Cancer; Protein Interactions; Radiotherapy Sensitivity

Numerous genetic changes occur as prostate cancer becomes more aggressive. We have shown that one such change is the loss of expression of CD9, a protein which is also lost in other human cancers. Re-introduction of CD9 into human prostate cancer cells i

随着前列腺癌变得更具侵袭性，会发生大量的基因变化。我们已经证明，其中一个变化是CD9的表达缺失，CD9是一种在其他人类癌症中也缺失的蛋白质。CD9基因重新导入人前列腺癌细胞的研究