Investigating the function of the LIM domain protein Zasp in muscle attachment and myofibril assembly

研究 LIM 结构域蛋白 Zasp 在肌肉附着和肌原纤维组装中的功能

• 批准号: 170772
• 负责人: Schöck Frieder
• 金额: $ 51.54万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=170772&lang=en
• 关键词: Cell-Matrix Adhesion; Developmental And Cell Biology; Drosophila; Genetic Screen; Muscle Attachment And Myofibril Assembly; Tissue Culture

We have identified the LIM domain protein Zasp, which is involved in connecting cells to their environment. This connection is mediated by integrins, proteins that sit in the plasma membrane surrounding each cell. Zasp carries a protein domain that target

我们已经确定了LIM结构域蛋白Zasp，它参与将细胞与其环境连接。这种连接是由整合素介导的，整合素是位于每个细胞周围的质膜上的蛋白质。Zasp携带一个蛋白质结构域，