Signaling mechanisms of the p75 neurotrophin receptor

p75 神经营养素受体的信号传导机制

• 批准号: 172558
• 负责人: Barker Philip A
• 金额: $ 68.13万
• 依托单位: Montreal Neurological Institute-Hospital
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=172558&lang=en
• 关键词: Apoptosis; Jun Kinase; Neurotrophin; Nf-Kb; Traf Proteins; Trk

Loss of neuronal cells is a hallmark of many diseases of the nervous system. and in many cases, this is mediated by loss of survival signals and activation of a process of cell suicide, termed apoptosis. My lab is concerned with identifying the precise ce

神经元细胞的丧失是许多神经系统疾病的标志。在许多情况下，这是由存活信号的丧失和细胞自杀过程（称为凋亡）的激活介导的。我的实验室致力于鉴定